I recently finished all six library edition volumes of Mike Mignola's Hellboy. Yes, I know: I'm late to the party. And, yes: I'm throwing in with his legion of admirers.
I keep coming back to these three panels from "Box Full of Evil" (1999) in Volume 2. I especially enjoy them out of context: they make the perfect little story. In his introduction to each volume, Mignola disclaims (retrospectively) any underlying vision to the series as it evolved. That might be true but it does not do justice to his firm command of narrative and the remarkable economy with which he paces a story.